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In contrast to phytoestrogens, these chemicals tend to bioaccumulate and induce persistent and refractory effects, even though their environmental concentrations oscillate in a relatively low range (Liu et al., 2012)

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By integrating photobiomodulation and biofeedback with remote monitoring platforms, ongoing CFS trials (NCT06145867, NCT05397626) seek to enhance patient engagement and adherence, thereby potentially improving treatment outcomes

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