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Description
Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors
Wu D, Chen C, Katoh K, Zhang J, Clarke IJ
Squire LR, Stark CE, Clark RE
Stewart, JM, et al
Consequently, the augmentation of low ergothioneine levels through supplementation appears to have no apparent safety concerns
