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They help separate the effects of the intervention from the effects of prediction, behaviour change and the many other factors that can improve wellbeing at the same time

doi: 10.1084/jem.2017fta

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Hybrid immunity versus hybrid harms: an immunologic paradox Once it became clear that the mRNA products could not provide durable sterilizing immunity, a new rationale emerged, one centered around the concept of hybrid immunity: the enhanced immunological responses resulting from the combined exposure to mRNA vaccination and the infection, producing stronger immunity when compared to either exposure alone