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Glutathione is an essential antioxidant and sulfur compound composed of three amino acidscysteine, glycine, and glutamic acidand is the major non-protein thiol in most organisms 1

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Types IV through VI require a more conservative approach because melanocytes in darker skin are more reactive to injury, including the controlled injury of a chemical peel

Reaven GM: Banting lecture 1988

Therefore, medications that affect these enzymatic pathways will influence melatonin metabolism