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Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S

Stockwell in 2012, describes a distinctive form of cell death characterized by iron-dependent phospholipid peroxidation, underscoring the pivotal role of glutathione peroxidase 4 (GPX4) in regulating this process

Lipid peroxidation refers to the process in which an oxygen or hydrogen peroxide molecule produces a hydroperoxy group, which is then inserted into a lipid molecule (Gaschler and Stockwell, 2017)

The solubility of the hydrophobic drugs could be enhanced using embedding in dendrimers (Zhang et al., 2011)

320,321 Additionally, NOX2-generated ROS are necessary for LC3 recruitment to phagosomes, revealing an autophagy-dependent antibacterial activity of NOX2 in phagocytes