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For example, this concept is supported by a study of dalotuzumab, the mTORC1 inhibitor ridaforolimus, and letrozole in hormone-sensitive breast cancer, in which the greatest anti-tumor effects were observed when all three drugs were combined [175]

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doi:10.1002/jbmr.2302 26

doi: 10.1007/s00787-017-0959-1

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