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Clin Chest Med

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Superoxide dismutase Superoxide dismutase (SOD) was discovered in 1969 by McCord and Fridovich (256) and forms the first line of defense against superoxide radicals as SOD dismutates superoxide radicals to form hydrogen peroxide (H 2 O 2 ) and oxygen (O 2 )

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This may be related to its ability to induce the formation of mitochondrial-derived vesicles through the PINK1/Parkin pathway, which participates in mitochondrial repair (187)

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2014;34:e00160

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The Alzheimers disease mitochondrial cascade hypothesis

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