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Acquired HER2 mutations in ER + metastatic breast cancer confer resistance to estrogen receptor-directed therapies
While necessary for fighting acute infection, this response generates vast quantities of reactive oxygen species (ROS)

PubMed, Weber, Heike, et al

Emodin alleviates intestinal mucosal injury in rats with severe acute pancreatitis via the caspase-1 inhibition

in total 32 genomes were sequenced at around 25x depth together with germline references (Fig
