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Hino K, Nishina S, Sasaki K, Hara Y
First, much of the mechanistic evidence derives from animal or cell-based studies, whereas human data are comparatively scarce and often limited to small cohorts or end-stage HF biopsies (Lopaschuk et al., 2010)

doi: 10.1084/jem.192.6.907

[DOI] [PMC free article] [PubMed] [Google Scholar] Linsdell P, Hanrahan JW

Consequently, treatment strategies for COPD should evolve from focusing solely on pulmonary function recovery to addressing its comorbidities simul-taneously[62]
