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For keeping up the treatment, injections are often given monthly

NMN measurement by HPLCMS NMN was measured as described in Tarrago et al

Precautions include avoiding use in those with cobalt allergy

doi: 10.1038/s41422-020-00417-1

Another source of deficiency can be malabsorption issues, where the body is unable to properly absorb B12 from the intestines due to various gastrointestinal disorders