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Increased oxidative stress and decreased antioxidant defense responses have been reported in HIV-positive patients 121

doi: 10.1016/S1875-5364(20)30036-4 101 YangW

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In this study, we found that LP promoted vascular endothelial cell migration and regulated NO via the activation of eNOS, thereby promoting angiogenesis both in vivo and in vitro

Deficiency of amino acids, glutathione reductase or glutathione peroxidase) Follow Oxidative and nitrosative (NO) stress Energy shortage Thiol group deficit (-SH) Detoxification disorders Immunosuppression and susceptibility to infection Reperfusion injury, increased hemolysis rates neurological, psychomotor, cardiovascular, ocular and hepatic disorders Glutathione diagnostics Nutritional and lifestyle history Specific symptoms Laboratory test Total glutathione (erythrocytes): 1805-3600 mol/l GSH reduced (leukocytes or erythrocytes): 962-3329 mol/l GSH:GSSG ratio (serum): 99:1 to 90:10 (no information about the intracellular situation) Glutathione peroxidase: 4170-10880 U/L In cases of stress/illness, the GSH/GSSG ratio shifts first