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But getting that last hour of the day, doing things to push down on cortisol, push down on stress, lower heart rate, not eating in that certainly that last hour before sleep, ideally 3 hours I feel like that small change can make an outsized positive difference

Regulation of mu-opioid receptors: desensitization, phosphorylation, internalization, and tolerance
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This, in turn, can make exercise and healthy eating easier and more sustainable over the long-term
