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This finding was confirmed by another follow-up study in 23 children with ADHD [47, 48]

At tissue-specific levels, piRNA modulates key signaling pathways both at transcription and translational levels

Over time, senescent cells secrete a variety of pro-inflammatory factors, collectively known as the senescence-associated secretory phenotype (SASP)

Additional biochemical evidence suggests that energy metabolite concentration could affect PTMs of the chromatin-modifying machinery itself, in turn regulating enzymatic activity, stability, and chromatin binding capacity associated with gene expression (54)