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98,100,103 Compared with those of CD8 + T cells, the diversity and output of CD4 + T cells are more stable, although some studies have indicated the accumulation of CD4 + T cells expressing PD-1 and Tregs (CD4 + CD25 + Foxp3 + ) during aging

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Additionally, it was demonstrated that EGT deficiency exacerbates the phenotype of the extremely sensitive mutant strain lacking Yap1 too ( egtA yap1 ) during treatment with oxidative stressors or metals

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ironlipid redox homeodynamics and ferroptosis assays