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In agreement with literature 59 , binding affinities were highest with ssDNA, followed by dsDNA and partial ssRNA and almost no binding to dsRNA, represented by SL1, with no difference between wt and D1467G for any variant RNA and DNA oligonucleotides (Supplementary Fig
If you have questions about which option is best for you, Dr
The bigger question is whether it does enough for the cost, and what realistic expectations are
Drug Research Related to Neuroactive Amino Acids, Alfred Benzon Symposium 32
Li F, Liu L
