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Targeting HIF-1 has therapeutic potential, but general inhibition should be avoided because HIF-1 has a the protective effect on mitochondria by reducing mitochondrial electron leakage and mito-stress (329)
Mller, T.D., et al
In this review, the search strategy, which used only three databases, one descriptor, and a Boolean combination, may have limited the retrieval of potentially relevant studies, despite the high number of articles initially evaluated (n = 542)
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