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Most studies involve small sample sizes and short follow-up durations, which weakens the statistical power for evaluating long-term safety despite supporting evidence from basic research

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Mirabegron, a Selective 3-Adrenergic Receptor Agonist, as a Potential Anti-Obesity Drug

The 2008 PhRMA report on Biotechnology Medicines identified 633 biotechnology products in developmental stages, of which 59 for autoimmune diseases, 254 for cancer, 34 for HIV/AIDS and related conditions, 162 for infectious diseases, 25 for cardiovascular disease, and 19 for diabetes and related conditions
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