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Another study confirmed that the combination of lpoeramide and pimozide triggers LMP by inhibiting the activity of sphingomyelin phosphodiesterase 1 (SMPD1), which affects the transport of lipids and cholesterol to lysosomes [184]

These are framed as may-support outcomes, not promises

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All individuals who as authors, consultants or advisers participate in the preparation of the EHC monograph must, in addition to serving in their personal capacity as scientists, inform the RO if at any time a conflict of interest, whether actual or potential, could be perceived in their work

26 Indeed, expressing EGFR in Schwann cells in transgenic mice leads to the formation of neurofibroma-like lesions (although at a very low penetrance), whereas an inactivating EGFR mutation decreases its tumorigenic potential in a mouse model of MPNST