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DOI:10.3390/antiox12010009 132

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The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression
Besides a broad application in the treatment of hepatic diseases, numerous preclinical and clinical studies over the last 2 decades demonstrated that SAMe showed promise in the treatment of critical neuropsychiatric diseases, including Alzheimers disease (AD) and major depression disorder (MDD) [7, 8]
