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Patient-derived xenograft The PDX experiment was approved by the Animal Ethical and Welfare Committee of the Sixth Affiliated Hospital, Sun Yat-sen University (Ethical code: IACUC-2021011501)

55-18-5 Reasonably anticipated to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as diethylnitrosamine Carcinogenicity N -Nitrosodiethylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals

Additionally, plasma MALAT1 levels are significantly lower in G allele carriers than in C allele carriers, suggesting that this polymorphism may influence hypertension development through lncRNA expression regulation [50]

Deaths may occur from overdosage with this class of drugs