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there are reports that ALA can lower circulating thyroid hormone (T3/T4) or reduce the efficacy of thyroid medications like levothyroxine, which means thyroid function should be monitored if ALA is used concurrently

Biomedicines, 13(10), 2483
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer

60 Under hemodynamic stress, autophagy is increased for cardioprotection, whereas loss of Atg5 causes spontaneous cardiomyopathy and stress vulnerability