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It is also important for brain and nerve cell function and development

Second and similarly, the search for the specific lipids that promote ferroptosis in a variety of contexts is ongoing, but it is clear that oxidized lipids have different capacities to promote ferroptosis, whereas some lipids, such as MUFAs, suppress ferroptosis

Thus, the upregulation of PRMT2 activates ferroptosis via the -catenin/GPX4 axis and participates in lipopolysaccharide-induced depressive behavior

More recently, the anticancer activity of new EA derivates has been tested in antiproliferative assays on two different tumoral cell lines 91