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Levodopa Levodopa has been shown in numerous placebo-controlled randomised trials to be effective in treating RLS (Limousin et al., 2018) levodopa was found to be useful in treating nocturnal symptoms of restless legs syndrome as well as improving both the subjective and objective quality of sleep-in patients with idiopathic and uraemic disease

After applying strict criteria for literature screening, we selected clinical trials focused on TMAO to determine its potential as a biomarker for specific disorders through the gut-organ axis

doi:10.1039/c9fo00449a

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CLA has possible effects on insulin sensitivity and L-carnitine requires renal clearance monitoring