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Some of these products have been traced to overseas manufacturing facilities operating without pharmaceutical-grade quality controls

By supporting the activity of gamma-aminobutyric acid (GABA), a key neurotransmitter, magnesium reduces overactivity in the brain and promotes a sense of calm, making it easier to fall asleep

NAD+: Enhances mitochondrial function, reduces oxidative stress, and supports cartilage integrity

doi: 10.1038/nsmb743

However, its important to note that many other more common conditions, including taking certain medications, are more likely to be the culprit: for example, a lack of dietary intake, taking medications for acid reflux or diabetes or an autoimmune condition, she adds