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In recent years, many studies have revealed that androgens can also regulate glucose and lipid metabolism upon binding to androgen receptors (AR) ( In addition to the gonadal organs, AR are also expressed in many major metabolic tissues, including the skeletal muscle, liver, pancreas, and brain, suggesting their important involvement in metabolism

2020;25(1):e12711

This hypothesis is supported by post-mortem evidence of reduced pyruvate dehydrogenase activity in the brains of individuals with ASD (Gu et al., 2013), which may impair the conversion of pyruvate to acetyl-CoA, leading to mitochondrial dysfunction and accumulation of lactate and alanine

Naturally produced in the body, L-carnitine plays a crucial role in human energy metabolism by enhancing -oxidation, a catabolic process by which fatty acids are broken down

and if the relative abundance of the qualitative ion(s) for each component in the sample is compared with the relative abundance of the corresponding qualitative ion(s) in a standard working solution of similar concentration, and the deviation does not exceed the range specified in the table below, then the corresponding analyte can be determined to be present in the sample