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The Wnt/-catenin pathway is also activated in DKD, and the inhibition of C3a/C5a was found to suppress EndMT and renal fibrosis via the Wnt/-catenin pathway in DKD [37]
Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation
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This shift is associated with reduced decomposition and enhanced carbon sequestration
