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Smoking exposure: Increases oxidative damage and drains the master antioxidant needed to protect cells
Accordingly, cuproptosis is limited by inhibitors of respiratory chain complexes I and III (rotenone and antimycin A, respectively), and an inhibitor of the mitochondrial pyruvate transporter (UK5099) [159,161]

The Pharmacopoeia of the Peoples Republic of China (China Medicine and Technology Publishing House, Beijing, 2010)

Notably, DWMLs are a recognized predictor for the development of impaired cognitive function and stroke [90,91]
