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Rec Nat Prod 5:158175 [Google Scholar] Gulcin I, Beydemir S, Topal F, Gagua N, Bakuridze A, Bayram R, Gepdiremen A (2012) Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst

showed that MTX-induced liver, kidney and heart damage was ameliorated with a flavonoid derivative diosmin (Reference Abdel-Daim, Khalifa and Abushouk47)

As a result, it cannot prevent contamination in the solution, leading to its early expiration

Acute high-altitude exposure also triggers hyperactivation of the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axes (Wang J
