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Increasing evidence suggests that IGFs play a crucial role in the development of PCa, including in the process of epithelial-mesenchymal transition (Kawada et al., 2006)

This study successfully developed a novel nanotherapeutic system, CDCZA, which combines curcumin and cisplatin within metal-organic framework nanocarriers to deplete glutathione and improve chemosensitivity, resulting in significant tumor suppression and minimal toxicity in vivo

Mitochondria sputter and stall, starving the cell of the energy it needs to survive
Organic solvent neurotoxicity: facts and research needs

Once inside cells, glutathione binds to free radicals, heavy metals, and toxins, converting them into harmless compounds that are eliminated by the liver and kidneys
