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Senescent mitochondria not only produce more ROS due to inefficient electron transport but also exhibit impaired iron-sulfur cluster biogenesis, leading to improper iron handling and accumulation within the mitochondria, thus creating a potent internal source of oxidative stress (106,107)
During oxidative phosphorylation, mitochondria produce ATP, and electron leakage during electron transport or NADPH oxidase on the cell membrane leads to the production of superoxide anions

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Signal transduction events triggered by adrenergic stimulation of BAT are effected via the activation of G s type G-proteins associated with the -adrenergic receptors

Buckley VA et al (2020): Outcomes following acute tocolysis prior to emergency caesarean section