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Given that somatic mutations in p53 typically arise later in tumor development, antioxidants may increase the progression of early tumors or precancerous lesions in high-risk groups, including smokers
[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Farokhnia M., Azarkolah A., Adinehfar F., Khodaie-Ardakani M.R., Hosseini S.M.R., Yekehtaz H., Tabrizi M., Rezaei F., Salehi B., Sadeghi S.M.R., et al
In research settings, effects are typically evaluated over structured study periods rather than immediately

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