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Although the pharmacology of VPA is still not understood completely, the drug seems to enhance activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), impair activity of the excitatory neurotransmitter glutamate, and block sodium channels

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Examples of medications that lower blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan) and diltiazem (Cardizem)

Iron homeostasis disruption also leads to changes in various adipokine concentrations, such as leptin and adiponectin, ultimately causing lipid metabolism disorders and insulin resistance

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