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enzyme-catalysed conjugations of glutathione with unsaturated compound doi Metabolism - an overview Conjugation With Glutathione and Mercapturic
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Epub 2014 Aug 13

doi: 10.1016/j.bbagen.2012.10.005

[DOI] [PMC free article] [PubMed] [Google Scholar] 133.Dixon S.J., Lemberg K.M., Lamprecht M.R., Skouta R., Zaitsev E.M., Gleason C.E., Patel D.N., Bauer A.J., Cantley A.M., Yang W.S., et al

There is another pathway that carries out this process using the enzyme betaine

The standard 4-6 weeks on, 2-4 weeks off pattern provides a structured approach even without specific data guiding these intervals
