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GLP-1R, widely distributed in the central nervous system, plays a crucial role in regulating various brain pathological processes, including neuroinflammation, nutrient metabolism, mitochondrial function, and synaptic function [50,51,52]

Sikiric, P., Boban Blagaic, A., Strbe, S., Beketic Oreskovic, L., Oreskovic, I., Suncana Sikiric, S., Staresinic, M., Sever, M., Kokot, A., Jurjevic, I., Matek, D., Coric, L., Krezic, I., Tvrdeic, A., Lueti, K., Batelja Vuleti, L., Pavic, P., Mestrovic, T., Sjekavica, I., & Skrtic, A

Discontinuation and reinitiation of dual-labeled GLP-1 receptor agonists among us adults with overweight or obesity

The links to cancer-related pathways cannot be ignored, and the absence of human safety data is glaring
