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Removal of its signal peptide during insertion into the endoplasmic reticulum generates proinsulin which consists of 3 domains: an amino-terminal B-chain, a carboxy-terminal A-chain and a connecting peptide known as C-peptide
10.1371/journal.pone.0065205 53 GarretnV.CarpinelliJ.JordanaX.HoluigueL
S.NgI.et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Corona G., Sansone A., Pallotti F., Ferlin A., Pivonello R., Isidori A.M., Maggi M., Jannini E.A
