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Ca 2 enters mitochondria via the mitochondrial calcium uniporter in the IMM, activating dehydrogenases in the tricarboxylic acid cycle and enhancing OXPHOS and ATP production, ensuring energy supply matches demand in cardiomyocytes and regulating synaptic transmission and plasticity in neurons

Increased pro-oxidant or decreased antioxidant defense is considered a promising therapeutic option as excessive ROS production beyond a threshold value leads to cancer cell death

Adipokines and endotoxemia correlate with hepatic steatosis in non-alcoholic fatty liver disease (NAFLD)

We did not detect the transfer of NHS-FITC + matrix in other organs (i.e., liver) from bleomycin-treated animals, nor in labeled lungs without bleomycin-treatment, excluding random diffusion of NHS-FITC + -matrix in the animals (Supplementary Fig

In vitro studies have shown that EGCG can inhibit cancer cell proliferation through various mechanisms, including cell cycle arrest and apoptosis induction