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These include nausea and vomiting [63], respiratory depression [64], and subsequently tolerance and dependence [65]

82 These findings suggest ASIC3 to be a useful target molecule for treatment of CDLBP

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Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction

Secondary outcomes The proportion of patients requiring percutaneous drainage was higher in the lavage group (sigmoidectomy 2/39 (5%) versus lavage 9/38 (24%), p = 0025)