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Ultraviolet radiation increases generation of reactive oxygen and nitrogen species, which in turn enhance tyrosinase activity and thereby synthesis of melanin species within cells
[DOI] [PubMed] [Google Scholar] 89.Schwartz JC, Arrang JM, Garbarg M, Pollard H, Ruat M
This moderate pressor effect is likely due to its nitric oxide scavenging effects 2 and this drug is sometimes used as an offlabel treatment for vasoplegic syndrome 3
