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However, overactivation or a failure to resolve their activation status (chronic activation from continued exposure to pro-inflammatory stimuli) can lead to the increased ECM deposition in the space of Disse that has a negative consequence for hepatocyte function and normal liver architecture, such as loss of microvilli [80,82]

32, S82S87

Circulation , 106:11541158

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[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Kera Y., Katoh Y., Ohta M., Matsumoto M., Takano-Yamamoto T., Igarashi K
