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Furthermore, the pathophysiological changes in ischemic stroke are a continuous and complex dynamic process involving energy impairment and ion imbalance, excitotoxicity of amino acids, oxidative stress, inflammatory responses, apoptosis and necrosis, reperfusion injury, and neuroregeneration and repair

Combination therapy is evaluated on a case-by-case basis, considering medical history, goals, and response to treatment

[4] [5] [6] Aripiprazole lauroxil was approved by the US Food and Drug Administration (FDA) in October 2015

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doi: 10.1016/j.mito.2006.03.002 133 SokoloviM.WehkampD.SokoloviA.VermeulenJ.Gilhuijs-PedersonL