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These findings suggest that research into the therapeutic modulation of FOXO4 activity, such as through the use of the synthetic peptide FOXO4-DRI, could provide insight into the heart's natural protective mechanisms and degenerative changes associated with aging

Notably, a more profound inhibitory effect was observed in the enriched cells with both expression vectors (Figure 6D)

Baldassarre S, Schandene L, Choufani G, Michils A: Asthma attacks induced by low doses of celecoxib, aspirin and acetaminophen