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These transporters belong to a family of proteins called the solute carriers

Biomaterials 29, 4757

According to reports, curcumin is a P450 inhibitor that inhibits CYP2C9, CYP1A2, CYP2D6, CYP2B6 and CYP3A4, with particularly low IC50 values for CYP2C9 (Appiah-Opong et al., 2007)

The extracellular matrix (ECM), traditionally considered a passive scaffold, is now recognised as an active metastasis promoter in target organs, making it a focus of recent studies (Figure 5), (Henke et al., 2020

Due to the toxic capacity of iron to overwhelm the antioxidant systems with ROS once free and overloaded, several proteins cater for iron, rendering most body iron protein bound