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Description
Primary structure of human microsomal dipeptidase deduced from molecular cloning
GPX4 represents the sole enzymatic system capable of reducing lipid hydroperoxides in mammalian cells, requiring reduced GSH as an essential cofactor for neutralizing lipid peroxides (LPOs)

In a randomized, open-label, controlled trial completed by 41 participants with PCOS, those who undertook lifestyle modification and received 30 grams flaxseed powder (about 2 tablespoons) per day for 12 weeks exhibited several improvements compared with lifestyle modifications alone

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Figueroa et al., 2017
