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Buse added that some data suggest adding cagrilintide could allow a lower dose of semaglutide with fewer unpleasant gastrointestinal side effects without sacrificing the benefits of glycemic management and weight loss

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The renal extraction and the natriuretic action of GLP-1 in Humans depend on interaction with the GLP-1 receptor

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Pharmacol Ther 109: 111, 2006 [DOI] [PubMed] [Google Scholar] 37.De Martin S, Orlando R, Bertoli M, Pegoraro P, Palatini P: Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis