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Long-term metformin use (the first-line type 2 diabetes drug) can lower B12 in a dose- and duration-dependent way: in the Diabetes Prevention Program Outcomes Study (Aroda and colleagues, The Journal of Clinical Endocrinology & Metabolism , 2016, roughly 1,700 participants), low B12 at 5 years occurred in 4.3 percent of metformin users versus 2.3 percent on placebo, and the gap widened with continued use

Recalls & Warnings January 22, 2026 Recalled Tuna Sold at Limited Retailers After Distribution Error On January 16, 2026, Tri-Union Seafoods warned consumers that limited quantities of Genova Yellowfin Tuna in Olive Oil and Genova Yellowfin Tuna in Extra Virgin Olive Oil with Sea Salt that were recalled in February 2025 due to botulism risk were inadvertently redistributed by a

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Vitamin B12 (Hydroxocobalamin) is a cobalt-containing essential vitamin central to red blood cell formation, nervous system function and methylation pathway support

Higher blood levels of glutathione have been associated with better health.*Help your body's natural processes run smoother than ever