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By definition, prodrugs are derivatives or precursors of therapeutically active molecules, which undergo bioconversion into their active form inside the body, be it via spontaneous processes (e.g., hydrolytic degradation) or through a biocatalytic mechanism

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[DOI] [PubMed] [Google Scholar] 33.Giustarini D, Galvagni F, Tesei A, Farolfi A, Zanoni M, Pignatta S, Milzani A, Marone IM, Dalle-Donne I, Nassini R, Rossi R

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These neuropsychiatric manifestations are often under-recognized and under-treated, yet they negatively affect daily functioning and overall well-being of PD patients 48,49,50

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In general, the mechanism of the HGF/c-Met pathway involvement in liver cancer requires more research, and c-Met inhibitors are a potential and promising therapeutic strategy in patients with HCC

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