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An adverse outcome pathway for decreased lung function focusing on mechanisms of impaired mucociliary clearance following inhalation exposure

Among nanoparticles of identical volume but of varying shapes and densities, pollen-like particles have shown superior performance for inhalation, owing in part to their inherent porosity, which improves aerosolization, flowability and deposition, all suited for inhaled drug delivery 132

KatA acts by converting hydrogen peroxide (H 2 O 2 ) into water (H 2 O) and molecular oxygen (O 2 )

Its use is limited to one year due to its association with increased incidence of cardiovascular and cerebrovascular events (eg, heart attack and stroke), as well as atypical femur fractures and osteonecrosis of the jaw

Approach to Obesity Treatment in Primary Care: A Review