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In humans, Menkes syndrome is a main manifestation of copper deficiency and causes serious neurological disorders (Danks et al., 1972

doi: 10.3389/fphar.2012.00059
Small HSPs as first responders to proteotoxic stress In contrast to HSP70 and HSP90, small heat shock proteins do not actively refold misfolded proteins
Microglia activation in central nervous system disorders: a review of recent mechanistic investigations and development efforts

(PubMed) Fernandez-Roig S, Lai SC, Murphy MM, Fernandez-Ballart J, Quadros EV
