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10.1038/ncomms2621 94 KrappA.DavidL

Safety depends on proper dosing, sourcing, and ongoing lab monitoring, which is why self-directed use is strongly discouraged

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Those effects are less prominent in the non-transformed MCF-10A cells, reflecting a favorable safety profile [74]

The molecular mechanism of tim overexpression promoted longevity might involve increased clock amplitude, de novo rhythmic genes, and/or circadian-independent roles of tim
