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When any component fails, oral supplementation becomes far less effective, potentially requiring massive doses to achieve therapeutic blood levels

doi: 10.3389/fpsyt.2021.703452

doi: 10.1016/j.lfs.2019.117045

A broader 2020 review by Sikiric and colleagues in Gut and Liver frames the compound's proposed GI activity within Robert's cytoprotection and organoprotection model the longstanding physiological framework describing how the gastric mucosa protects itself against injury

Hemery, Y
